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  • Term: magnesium citrate
    Key Words: ,
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    magnesium citrate!


    magnesium citrate

    Comprehensive Analysis



    1) "Magnesium" -- As to magnesium citrate

    magnesium
    Pronunciation: mag-'nE-zE-&m, -zh&m
    Function: noun
    Etymology: New Latin, from magnesia
    : a silver-white malleable ductile light metallic element that occurs abundantly in nature and is used in metallurgical and chemical processes, in photography, signaling, and pyrotechnics because of the intense white light it produces on burning, and in construction especially in the form of light alloys -- see ELEMENT table
    Pronunciation Symbols

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    2) "Citrate" -- As to magnesium citrate

    citrate
    Pronunciation: 'si-"trAt
    Function: noun
    Etymology: International Scientific Vocabulary
    : a salt or ester of citric acid
    Pronunciation Symbols

    Chemical structure of citric acid.

    A citrate is an ionic form of citric acid, such as C3H5O(COO)33−, that is, citric acid minus three hydrogen ions.

    Citrates are compounds containing this group, either ionic compounds, the salts, or analogous covalent compounds, esters. An example of a salt is sodium citrate and an ester is trimethyl citrate. See category for a bigger list.

    Since citric acid is a multifunctional acid, intermediate ions exist, hydrogen citrate ion, HC6H5O72− and dihydrogen citrate ion, H2C6H5O7. These may form salts as well, called acid salts.

    Salts of the hydrogen citrate ions are weakly acidic, while salts of the citrate ion itself (with an inert cation such as sodium ion) are weakly basic.

    Citrate is a key component in the commonly used SSC 20X hybridization buffer. There exists authoritative literature (Maniatis) that incorrectly instructs the preparation of this buffer to include 3M NaCl and 0.3M Sodium Citrate, to be titrated up with NaOH to a pH of 7. When the two components are actually mixed together, the pH is slightly basic. Therefore, the pH of the solution should instead be titrated down to 7 with HCl.

    12 sodium ← magnesium → aluminium
    Be

    Mg

    Ca
    General
    Name, Symbol, Number magnesium, Mg, 12
    Chemical series alkaline earth metals
    Group, Period, Block 2, 3, s
    Appearance silvery white
    Atomic mass 24.3050(6)  g·mol−1
    Electron configuration [Ne] 3s2
    Electrons per shell 2, 8, 2
    Physical properties
    Phase solid
    Density (near r.t.) 1.738  g·cm−3
    Liquid density at m.p. 1.584  g·cm−3
    Melting point 923 K
    (650 °C, 1202 °F)
    Boiling point 1363 K
    (1090 °C, 1994 °F)
    Heat of fusion 8.48  kJ·mol−1
    Heat of vaporization 128  kJ·mol−1
    Heat capacity (25 °C) 24.869  J·mol−1·K−1
    Vapor pressure
    P(Pa) 1 10 100 1 k 10 k 100 k
    at T(K) 701 773 861 971 1132 1361
    Atomic properties
    • 1 Metabolism
      • 1.1 TCA cycle
      • 1.2 Role in Glycolysis
    • 2 See also

    Citrate is an intermediate in the TCA (Krebs) Cycle. After the pyruvate dehydrogenase complex forms acetyl CoA, from pyruvate and five cofactors (Thiamine pyrophosphate, lipoamide, FAD, NAD+, and CoA), citrate synthase catalyzes the condensation of oxaloacetate with Acetyl CoA to form citrate. Citrate continues in the TCA cycle with the eventual regeneration of oxaloacetate, which can combine with another molecule of acetyl CoA and continue cycling.

    See also TCA cycle

    High concentration of citrate can ..."



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